Zinciriye Madrasa (Turkish Zinciriye Medresesi) also known as Sultan Isa Madrasa is one of the most beautiful historical sights in the old part of Mardin. It was build in 1385 Melik Necmeddin Isa bin Muzaffer Davud bin El Melik Salih. He was last Sultan from the Artuqid dynasty ruling in Mardin. The basic principles of the original Mardin architectural style were formed in the time of the Artuqids.
Located southwest of the old part of city Kasımiye Medrese is amongst the most significant historical sights of Mardin. Also its one of the best examples of the local Artuklu architecture style. The edifice is interesting due to its design, masonry and ornamentation.
This zawiya was build on the small hill in the memory of Imam Abdullah, which comes from the descent of the Islamic prophet Muhammad. He was very respected by people so his tomb was extended and became a kulliye.